A kind of chronic inflammatory condition known as synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is uncommon and challenging to cure. SAPHO syndrome's principal clinical presentation is osteoarthropathy with cutaneous involvement. It is hypothesized that genetic variations across individuals, immune systems, microbes, and environmental variables are associated with the pathophysiology of SAPHO syndrome, which is still unknown. A new small-molecule Janus kinase inhibitor called tofacitinib has been utilized to treat rheumatoid arthritis disease. But it also holds a lot of promise for treating other immunological disorders, such SAPHO syndrome.
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